Medically Reviewed By Dr Kirti Bishnoi (Gynecologist)
In women’s health and fertility care, progesterone sustained release (SR) tablets have become an important treatment. These tablets help release the hormone slowly over time, matching how the body normally works.
But what are they really used for? Who should take them — and who should avoid them? Let’s break it down in a simple and clear way.

What Are Progesterone Sustained Release Tablets?
Progesterone SR tablets are hormone medicines that release progesterone slowly through the day. This helps keep your hormone level steady and gives better results for problems like irregular periods or pregnancy support.
Doctors often give these tablets for:
- Fertility treatments (like IVF or IUI)
- Missed periods
- Hormone replacement during menopause
- Early pregnancy support
Why Is Progesterone Important?
Progesterone is a natural hormone that helps with regular periods and pregnancy. It thickens the womb lining and helps keep a pregnancy in its early weeks.
If your body doesn’t make enough progesterone, you might face:
- Irregular or missed periods
- Trouble getting pregnant
- Early miscarriage
Sustained release progesterone tablets give your body the hormone it needs in a steady way.
What Are These Tablets Used For?
1. Fertility Support (IVF/IUI)
After ovulation or embryo transfer, progesterone helps the womb prepare for a baby and hold the pregnancy.
2. Early Pregnancy Loss
It helps relax the womb muscles and keeps the lining strong, lowering the risk of miscarriage.
3. PCOS and Missed Periods
In women with PCOS or missed periods, progesterone helps trigger a normal monthly bleed.
4. Menopause Support (HRT)
Women on estrogen therapy after menopause also need progesterone to protect the womb lining.
Progesterone Sustained Release Tablets Uses In Hindi
Progesterone sustained release tablets ek special type ki hormone medicine hai jo dheere-dheere body mein hormone release karti hai. Ye tablets mainly women ke liye use hoti hai, especially IVF, IUI ya early pregnancy mein uterus ko strong banane aur miscarriage se bachane ke liye. Ye PCOS aur irregular periods mein bhi di jati hai. Menopause ke baad hormone replacement therapy mein bhi iska use hota hai. SR tablets din bhar hormone ko steady banaye rakhti hain, jisse better results milte hain. Doctor ki salah ke bina ise na lein, aur tablet ko kabhi todkar ya chabakar na khaayein.
How Do These Tablets Work?
Progesterone SR tablets give natural progesterone in a slow and steady way over 24 hours. This avoids sharp ups and downs in hormone levels.
They help:
- Prepare the womb lining
- Lower womb contractions
- Support a pregnancy
- Keep hormones balanced
Dosage and Duration
Important: Always take progesterone after your doctor’s advice.
Why It’s Used | Normal Dose | How Long to Take |
---|---|---|
IVF/IUI Support | 200–300 mg once daily | Until 10–12 weeks of pregnancy |
Missed Periods/PCOS | 200 mg for 5–10 days | As advised by the doctor |
Hormone Therapy (HRT) | 200 mg at bedtime | Days 14–25 of your cycle |
Tip: Take the tablet after a meal, best at bedtime, to avoid nausea or dizziness.
SR Tablets vs Other Types of Progesterone
Type | How It’s Taken | Lasts For | Pros |
---|---|---|---|
SR Tablets | By mouth | 24 hours | Easy, once-a-day dose |
Soft Gel Capsules | Mouth/Vaginal | 12 hours | Quick and flexible |
Injections | Injection | 2–3 days | Stronger, but may cause pain |
Vaginal Gel | Vaginal | 12–24 hours | Works locally, fewer side effects |
Common Side Effects
Most people take progesterone tablets without serious problems. But some may feel:
Mild Side Effects:
- Feeling sick or bloated
- Sleepiness or light-headedness
- Mood changes
- Breast pain
- Headache
- Vaginal discharge
Rare but Serious:
- Blood clots
- Liver issues
- Allergic reactions
Call your doctor if you have swelling, chest pain, yellowing of skin/eyes, or bad headaches.
Who Should Avoid These Tablets?
Avoid taking these tablets if you have:
- Past blood clots or stroke
- Liver problems
- Breast cancer
- Unknown vaginal bleeding
- Allergy to progesterone
Only take during pregnancy if your doctor says it’s safe.
Are These Tablets Safe in Pregnancy and Breastfeeding?
Yes, doctors often use them in early pregnancy to:
- Lower the risk of miscarriage
- Help in IVF/IUI cycles
- Support the womb lining
They are generally safe during breastfeeding, but always check with your doctor first.
Popular Brands in India (2025)
Here are some trusted brands:
- Susten SR 200 / 300 (Sun Pharma)
- Gestofit SR
- Naturogest SR
- Dubagest SR
- Endogest SR
- LupiPro SR
- Progesterone Sustafem
- Proluton SR
These are prescription-only medicines. Don’t take them on your own.
What Is Sustained Release Tablets?
Sustained release (SR) tablets are special types of medicines that slowly release the drug in your body over many hours. Instead of taking the same medicine 2–3 times a day, these tablets work for a long time with just one or two doses.
These tablets have a special outer layer or formula that controls how fast the medicine is released. This helps keep the amount of medicine in your blood steady, which can give better results and fewer side effects.
SR tablets are used for health problems like high blood pressure, diabetes, low mood (depression), and hormone problems. For example, progesterone sustained release tablets are often given to women to help during pregnancy or to fix hormone imbalances. They release the hormone slowly, just like the body’s natural way.
Benefits of SR tablets:
- You take them less often
- Better control of symptoms
- Easy to follow the treatment
But remember: Do not crush or chew SR tablets. Breaking them can release too much medicine at once and may harm you. Always take them whole, with water, and follow your doctor’s advice.
Sustained release tablets make treatment simple, steady, and safe when used the right way.
Common Questions
Q1. What are progesterone sustained release tablets 300 mg?
Progesterone sustained release tablets 300 mg are medication that slowly releases progesterone into the bloodstream. They help regulate menstrual cycles, support early pregnancy, and treat hormone imbalances. Always use under medical guidance to ensure safe and effective hormone therapy.
Q2. Can I take progesterone SR tablets without seeing a doctor?
No. These are hormone medicines. Only a doctor can decide if you need them.
Q3. What if I forget to take a dose?
Take it as soon as you remember. If it’s close to your next dose, skip it. Don’t take two at once.
Q4. How long do I take progesterone in pregnancy?
Usually up to 10–12 weeks. Your doctor will guide you.
Q5. Can food or lifestyle replace this medicine?
Healthy food and habits help balance hormones, but this medicine is often needed in medical treatments.

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