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My Experience with Progesterone SR Tablets in Hormonal Imbalance, Pregnancy Support & Fertility Treatments

Posted on June 2, 2025

Medically Reviewed By Dr Kirti Bishnoi (Gynecologist)

In women’s health and fertility care, progesterone sustained release (SR) tablets have become an important treatment. These tablets help release the hormone slowly over time, matching how the body normally works.

But what are they really used for? Who should take them — and who should avoid them? Let’s break it down in a simple and clear way.

Progesterone Sustained Release Tablets
Progesterone Sustained Release Tablets: Uses, Side Effects, Dosages

What Are Progesterone Sustained Release Tablets?

Progesterone SR tablets are hormone medicines that release progesterone slowly through the day. This helps keep your hormone level steady and gives better results for problems like irregular periods or pregnancy support.

Doctors often give these tablets for:

  • Fertility treatments (like IVF or IUI)
  • Missed periods
  • Hormone replacement during menopause
  • Early pregnancy support

Why Is Progesterone Important?

Progesterone is a natural hormone that helps with regular periods and pregnancy. It thickens the womb lining and helps keep a pregnancy in its early weeks.

If your body doesn’t make enough progesterone, you might face:

  • Irregular or missed periods
  • Trouble getting pregnant
  • Early miscarriage

Sustained release progesterone tablets give your body the hormone it needs in a steady way.

What Are These Tablets Used For?

1. Fertility Support (IVF/IUI)

After ovulation or embryo transfer, progesterone helps the womb prepare for a baby and hold the pregnancy.

2. Early Pregnancy Loss

It helps relax the womb muscles and keeps the lining strong, lowering the risk of miscarriage.

3. PCOS and Missed Periods

In women with PCOS or missed periods, progesterone helps trigger a normal monthly bleed.

4. Menopause Support (HRT)

Women on estrogen therapy after menopause also need progesterone to protect the womb lining.

Progesterone Sustained Release Tablets Uses In Hindi

Progesterone sustained release tablets ek special type ki hormone medicine hai jo dheere-dheere body mein hormone release karti hai. Ye tablets mainly women ke liye use hoti hai, especially IVF, IUI ya early pregnancy mein uterus ko strong banane aur miscarriage se bachane ke liye. Ye PCOS aur irregular periods mein bhi di jati hai. Menopause ke baad hormone replacement therapy mein bhi iska use hota hai. SR tablets din bhar hormone ko steady banaye rakhti hain, jisse better results milte hain. Doctor ki salah ke bina ise na lein, aur tablet ko kabhi todkar ya chabakar na khaayein.

How Do These Tablets Work?

Progesterone SR tablets give natural progesterone in a slow and steady way over 24 hours. This avoids sharp ups and downs in hormone levels.

They help:

  • Prepare the womb lining
  • Lower womb contractions
  • Support a pregnancy
  • Keep hormones balanced

Dosage and Duration

Important: Always take progesterone after your doctor’s advice.

Why It’s Used Normal Dose How Long to Take
IVF/IUI Support 200–300 mg once daily Until 10–12 weeks of pregnancy
Missed Periods/PCOS 200 mg for 5–10 days As advised by the doctor
Hormone Therapy (HRT) 200 mg at bedtime Days 14–25 of your cycle

Tip: Take the tablet after a meal, best at bedtime, to avoid nausea or dizziness.

SR Tablets vs Other Types of Progesterone

Type How It’s Taken Lasts For Pros
SR Tablets By mouth 24 hours Easy, once-a-day dose
Soft Gel Capsules Mouth/Vaginal 12 hours Quick and flexible
Injections Injection 2–3 days Stronger, but may cause pain
Vaginal Gel Vaginal 12–24 hours Works locally, fewer side effects

Common Side Effects

Most people take progesterone tablets without serious problems. But some may feel:

Mild Side Effects:

  • Feeling sick or bloated
  • Sleepiness or light-headedness
  • Mood changes
  • Breast pain
  • Headache
  • Vaginal discharge

Rare but Serious:

  • Blood clots
  • Liver issues
  • Allergic reactions

Call your doctor if you have swelling, chest pain, yellowing of skin/eyes, or bad headaches.

Who Should Avoid These Tablets?

Avoid taking these tablets if you have:

  • Past blood clots or stroke
  • Liver problems
  • Breast cancer
  • Unknown vaginal bleeding
  • Allergy to progesterone

Only take during pregnancy if your doctor says it’s safe.

Are These Tablets Safe in Pregnancy and Breastfeeding?

Yes, doctors often use them in early pregnancy to:

  • Lower the risk of miscarriage
  • Help in IVF/IUI cycles
  • Support the womb lining

They are generally safe during breastfeeding, but always check with your doctor first.

Popular Brands in India (2025)

Here are some trusted brands:

  • Susten SR 200 / 300 (Sun Pharma)
  • Gestofit SR
  • Naturogest SR
  • Dubagest SR
  • Endogest SR
  • LupiPro SR
  • Progesterone Sustafem
  • Proluton SR

These are prescription-only medicines. Don’t take them on your own.

What Is Sustained Release Tablets?

Sustained release (SR) tablets are special types of medicines that slowly release the drug in your body over many hours. Instead of taking the same medicine 2–3 times a day, these tablets work for a long time with just one or two doses.

These tablets have a special outer layer or formula that controls how fast the medicine is released. This helps keep the amount of medicine in your blood steady, which can give better results and fewer side effects.

SR tablets are used for health problems like high blood pressure, diabetes, low mood (depression), and hormone problems. For example, progesterone sustained release tablets are often given to women to help during pregnancy or to fix hormone imbalances. They release the hormone slowly, just like the body’s natural way.

Benefits of SR tablets:

  • You take them less often
  • Better control of symptoms
  • Easy to follow the treatment

But remember: Do not crush or chew SR tablets. Breaking them can release too much medicine at once and may harm you. Always take them whole, with water, and follow your doctor’s advice.

Sustained release tablets make treatment simple, steady, and safe when used the right way.

Common Questions

Q1. What are progesterone sustained release tablets 300 mg?
Progesterone sustained release tablets 300 mg are medication that slowly releases progesterone into the bloodstream. They help regulate menstrual cycles, support early pregnancy, and treat hormone imbalances. Always use under medical guidance to ensure safe and effective hormone therapy.

Q2. Can I take progesterone SR tablets without seeing a doctor?
No. These are hormone medicines. Only a doctor can decide if you need them.

Q3. What if I forget to take a dose?
Take it as soon as you remember. If it’s close to your next dose, skip it. Don’t take two at once.

Q4. How long do I take progesterone in pregnancy?
Usually up to 10–12 weeks. Your doctor will guide you.

Q5. Can food or lifestyle replace this medicine?
Healthy food and habits help balance hormones, but this medicine is often needed in medical treatments.

Dr Ashish Panwar
Dr. Ashish Panwar

Hello, I am Dr. Ashish. I have lot of experience in medical field and education, I have gained lot of knowledge in my entrance exam life and medical studies which I want to share with everyone so that I can help more and more people.

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